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The onset of antagonism may be delayed in the presence of debilitation cachexia carcinomatosis and the concomitant use of certain broad spectrum antibiotics or anesthetic agents and other drugs which enhance neuromuscular block or separately cause respiratory depression see PRECAUTIONS Drug Interactions.
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Abacavir Isolates containing abacavir resistance associated amino acid substitutions namely K65R L74V Y115F and M184V exhibited cross resistance to didanosine emtricitabine lamivudine tenofovir and zalcitabine in cell culture and in subjects.
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VascularDisorders Peripheral vasculitis gangrene and capillary leak syndrome see Warnings and Precautions 5. Safety information was obtained in 1173 patients during double blind and open monday clinical trials including neuropathic pain conditions for which efficacy has not been demonstrated.
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An increase in exposure of enoxaparin sodium with reduced dosages non weight adjusted has been observed in low weight women 45 kg and low weight men 57 kg.