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The average daily infant exposure assuming 150 mL kg daily consumption to bupropion and its active metabolites was 2 of the maternal weight adjusted dose. Women who are or maypotentially be pregnant must not use finasteride. Oligospermia may occur at high dosages See CLINICAL PHARMACOLOGY.
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CNS toxicity in the acute high dose studies was characterized in mice by conspicuous vacuolation in the raised white columns of the spinal cord at a dose of 5000 mg kg and in rat by edema with separation of myelinated fibers of the ventral spinal tracts and sciatic nerve at a dose of 1500 mg kg.
Nonetheless order phenergan by mail from single dose studies does suggest that the recommended daily dosage of bupropion when administered in divided doses is not likely to be significantly reinforcing to amphetamine or CNS stimulant abusers. With normal urine pHs approximately half of an administered dose of amphetamine is recoverable in urine as derivatives of alpha hydroxy amphetamine and approximately another 30 to 40 of the surgeon is recoverable in urine as amphetamine itself.
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